Reconstruction of myocardial tissue motion and strain fields from displacement-encoded MR imaging

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Reconstruction of myocardial tissue motion and strain fields from displacement-encoded MR imaging.

A quantitative analysis of myocardial mechanics is fundamental to understanding cardiac function, diagnosis of heart disease, and assessment of therapeutic intervention. Displacement encoding with stimulated-echo (DENSE) magnetic resonance imaging (MRI) technique was developed to track the three-dimensional (3D) displacement vector of discrete material grid points in the myocardial tissue. Desp...

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Myocardial strains from 3D displacement encoded magnetic resonance imaging

BACKGROUND The ability to measure and quantify myocardial motion and deformation provides a useful tool to assist in the diagnosis, prognosis and management of heart disease. The recent development of magnetic resonance imaging methods, such as harmonic phase analysis of tagging and displacement encoding with stimulated echoes (DENSE), make detailed non-invasive 3D kinematic analyses of human m...

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Spatially resolved imaging of myocardial function with strain-encoded MR: comparison with delayed contrast-enhanced MR imaging after myocardial infarction.

Strain-encoded magnetic resonance (MR) imaging was prospectively evaluated for direct imaging of systolic myocardial strain and compared with cross-registered delayed contrast material-enhanced MR imaging in five healthy volunteers and nine patients with infarction. Local contractile performance was decreased in infarcted myocardium versus that in remote and adjacent myocardium (P < .01) and in...

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Simultaneous myocardial strain and dark-blood perfusion imaging using a displacement-encoded MRI pulse sequence.

The purpose of this study is to develop and evaluate a displacement-encoded pulse sequence for simultaneous perfusion and strain imaging. Displacement-encoded images in two to three myocardial slices were repeatedly acquired using a single-shot pulse sequence for 3 to 4 min, which covers a bolus infusion of Gadolinium contrast. The magnitudes of the images were T(1) weighted and provided quanti...

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Quantitative assessment of myocardial motion from displacement measurements derived from velocity encoded MRI

Methods 12 volunteers (30±8 years) and 3 patients (41±11 years) were investigated at a 3T whole body MR scanner (Achieva, Philips) with a 32 channel coil. The patients suffer from DCM, asynchrony and/or LBBB. A velocity encoded navigated segmented gradient echo sequence was applied in the apical, equatorial and basal slice. Acquisition parameters: FOV=340mm, in-plane res. =2.5mm, slice thicknes...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology

سال: 2009

ISSN: 0363-6135,1522-1539

DOI: 10.1152/ajpheart.00074.2009